Dr. Samuel Klein

MD, Gastroenterology, Diabetes, and Obesity Medicine

Dr. Klein is the William H. Danforth Professor of Medicine, Director of the Center for Human Nutrition, Director of the Center for Applied Research Sciences, and Chief of the Division of Geriatrics and Nutritional Sciences at Washington University School of Medicine in St. Louis, Missouri. Dr. Klein received an MD degree from Temple University Medical School, and an MS Degree in Nutritional Biochemistry and Metabolism from the Massachusetts Institute of Technology. He completed residency training in Internal Medicine and a Clinical Nutrition fellowship at Boston University Hospital, a Nutrition and Metabolism Research fellowship at Harvard Medical School, and a Gastroenterology fellowship at The Mt. Sinai Medical Center in New York. He is board certified in Internal Medicine, Gastroenterology, and Nutrition. Samuel Klein MD also serves as Sansum Diabetes Research Institute’s Chief Scientific Officer.

Dr. Klein has had consistent funding from the National Institutes of Health since 1990, and has published more than 400 papers in nutrition, obesity and diabetes. He has received numerous awards for his research, including the American Gastroenterological Association (AGA) Miles and Shirley Fiterman Foundation Award in Nutrition, the AGA Masters Award for Outstanding Achievement in Basic or Clinical Research in Digestive Sciences, the AGA Obesity, Metabolism & Nutrition Research Mentor Award, the Academy of Science-St. Louis Award for Outstanding Achievement in Science, the American Society for Nutrition Robert H. Herman Award, the American Society for Parenteral and Enteral Nutrition George Blackburn Research Mentorship Award, and The Obesity Society TOPS Research Achievement Award, George A. Bray Founders Award, and the George L. Blackburn Award for Excellence in Obesity Medicine.

Dr. Klein’s research is characterized by the use of stable isotope tracers and cellular analysis of tissue samples in studies conducted in human subjects to simultaneously evaluate cellular, regional, and whole-body substrate metabolism. His laboratory is particularly interested in the mechanisms responsible for the metabolic abnormalities associated with obesity.